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Lilly Straps on Barrel, Jumps Into Niagara River 13 Jul 2013 | 12:08 am

Upstream, that is. Today Eli Lilly announced that is plunging ahead with further development of solanezumab in Alzheimer disease, despite the drug's tepid performance in 2 previous phase 3 trials (EXP...

NYT Outs Bayonne Med Center as Highest-Charging Hospital 21 May 2013 | 10:49 pm

An admittedly late notice. (The NYT report was published 5 days ago.)But the paper provides an important insight into why some high-fee hospitals charge what they charge, especially when they claim th...

Double Effing News Flash: Hospital Fees Inconsistent and Inexplicable 8 May 2013 | 08:02 pm

Newly released data from the Center for Medicare and Medicaid Services show that the nation's hospitals charge wildly different fees for the same procedure. (See the NYT story here.) And while that in...

IV Ig a Bust in Alzheimer's 7 May 2013 | 08:59 pm

Possibly the last immunotherapy hope in established Alzheimer disease, intravenous gamma globulin (aka IV Ig) failed to slow cognitive decline in a large, closely watched phase 3 trial. According to t...

Many Early 20th Century US Medical Journals May Be in Public Domain 26 Apr 2013 | 11:08 pm

For those of us interested in writing about medical history, particularly early 20th-century medical history, a specific hurdle is encountered when attempting to quote, extract, or reprint text, figur...

Americans With Alzheimer Disease Will Nearly Triple by 2050 7 Feb 2013 | 08:02 pm

A new census-based study, published online in Neurology, indicates that the number of people with Alzheimer disease in 2010 was 4.7 million. This number is projected to increase to nearly 14 million (...

Lilly's Solanezumab Picked for Alzheimer Prevention Study 19 Jan 2013 | 03:01 am

Despite the fact that Lilly's solanezumab failed in recent phase 3 trials (and despite vigorous attempts to pound out convincing clinical and biomarker data), the anti-amyloid MAb will be assessed in ...

Official News of Hillary Clinton's Medical Condition Is Confusing 31 Dec 2012 | 08:57 pm

I concur with Richard Bazell, NBC's head science reporter, that information dispensed from the State Department about Hillary Clinton's medical condition is very confusing. The given and widely report...

Once More Into the Breach: Lilly Plans New Phase 3 Study of Anti-Amyloid MAb in Alzheimer's 13 Dec 2012 | 12:45 am

Despite tepid phase 3 results (see here and here), Lilly will continue late-phase development of its anti-amyloid MAb, solanezumab, in patients with mild AD. Today's company press release says that th...

Alzheimer Drugs in Development: The (Sad-ish) State of Affairs 10 Dec 2012 | 10:45 pm

Merck's recent announcement of the clinical development of its BACE1 inhibitor, MK-8931, into phase 2 study in Alzheimer disease met with head-scratching fanfare. Nevertheless the news provides an opp...

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