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Poly(D-lactide)/poly(caprolactone) nanofiber-thermogelling chitosan gel composite scaffolds for osteochondral tissue regeneration in a rat model 12 Mar 2013 | 08:42 am
Macroporous nanostructured scaffolds that can be made to closely mimic skeletal tissue extracellular matrix as well as have the potential to support bone and cartilage tissue regeneration. Porous poly...
Self-cross-linkable hydrogels composed of partially oxidized alginate and gelatin for myocardial infarction repair 12 Mar 2013 | 08:42 am
Calcium cross-linked alginate hydrogel has shown positive results for the treatment of myocardial infarction in both acute and chronic rat models. However, cross-linked alginate hydrogels possess poor...
Electrospun poly(lactic-co-glycolic acid)/wool keratin fibrous composite scaffolds potential for bone tissue engineering applications 12 Mar 2013 | 08:42 am
Biocomposite scaffolds consist of poly(lactic- co -glycolic acid) and wool keratin were obtained by an electrospinning process. Scanning electron microscopy images showed that the poly(lactic- co -gly...
Functionalization of electrospun poly({varepsilon}-caprolactone) scaffold with heparin and vascular endothelial growth factors for potential applicati... 12 Mar 2013 | 08:42 am
In this study, a heparin-conjugated poly(-caprolactone) electrospun fiber was constructed to develop a functional scaffold for controlled release of vascular endothelial growth factors. The immobiliza...
Highly sensitive gold-overoxidized polypyrrole nanocomposite immunosensor for antitransglutaminase antibody 12 Mar 2013 | 08:42 am
Patients with coeliac disease, a gluten intolerance autoimmune disorder, have elevated levels of antitransglutaminase antibody in their human sera. In this study, an immunosensor for the electrochemic...
Physical and biological effects of gellan gum on decreasing postoperative adhesion in a rat model 12 Mar 2013 | 08:42 am
An antiadhesion membrane made from gellan gum was fabricated and characterized. A 12-µm-thick membrane of gellan gum was prepared and reacted with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide to obt...
Polymer chains incorporating caprolactone and arginine-glycine-aspartic acid functionalities: Synthesis, characterization and biological response in v... 16 Jan 2013 | 07:31 am
This study describes a strategy for the covalent immobilization of active adhesion peptide moieties onto polymers through the intermediacy of itaconic acid. The arginine–glycine–aspartic acid peptide ...
Thermosensitive poly(N-isopropyl acrylamide-co-N,N-dimethyl acryl amide)-block-poly(D,L-lactide) amphiphilic block copolymer micelles for prednisone d... 16 Jan 2013 | 07:31 am
Novel amphiphilic block copolymers consisting of hydrophobic poly( D , L -lactide) segments and hydrophilic poly( N -isopropylacrylamide- co - N, N -dimethylacrylamide) blocks were designed and synthe...
Rapid disinfection by N-halamine polyelectrolytes 16 Jan 2013 | 07:31 am
Two new N-halamine polyelectrolytes were synthesized, characterized, and deposited onto cotton fabric from a water solution using a layer-by-layer assembly technique. The fabrics were rendered biocida...
Studies on the biocompatibility of bacterial cellulose 16 Jan 2013 | 07:31 am
Bacterial cellulose was functionalized with a chimeric protein containing a cellulose-binding module and the adhesion peptide Arg-Gly-Asp. Small-diameter bacterial cellulose membranes were produced an...
