Editorial Board [Masthead] 14 Aug 2013 | 12:54 am

Conserved Regions of Gonococcal TbpB Are Critical for Surface Exposure and Transferrin Iron Utilization [Molecular Pathogenesis] 14 Aug 2013 | 12:54 am

The transferrin-binding proteins TbpA and TbpB enable Neisseria gonorrhoeae to obtain iron from human transferrin. The lipoprotein TbpB facilitates, but is not strictly required for, TbpA-mediated iro...

Dectin Immunoadhesins and Pneumocystis Pneumonia [Fungal and Parasitic Infections] 14 Aug 2013 | 12:54 am

The opportunistic pathogen Pneumocystis jirovecii is a significant cause of disease in HIV-infected patients and others with immunosuppressive conditions. Pneumocystis can also cause complications in ...

Sterile-{alpha}- and Armadillo Motif-Containing Protein Inhibits the TRIF-Dependent Downregulation of Signal Regulatory Protein {alpha} To Interfere w... 14 Aug 2013 | 12:54 am

Burkholderia pseudomallei, the causative agent of melioidosis, evades macrophage killing by suppressing the TRIF-dependent pathway, leading to inhibition of inducible nitric oxide synthase (iNOS) expr...

SdiA Aids Enterohemorrhagic Escherichia coli Carriage by Cattle Fed a Forage or Grain Diet [Molecular Pathogenesis] 14 Aug 2013 | 12:54 am

Enterohemorrhagic Escherichia coli (EHEC) causes hemorrhagic colitis and life-threatening complications. The main reservoirs for EHEC are healthy ruminants. We reported that SdiA senses acyl homoserin...

Serine Lipids of Porphyromonas gingivalis Are Human and Mouse Toll-Like Receptor 2 Ligands [Host Response and Inflammation] 14 Aug 2013 | 12:54 am

The total cellular lipids of Porphyromas gingivalis, a known periodontal pathogen, were previously shown to promote dendritic cell activation and inhibition of osteoblasts through engagement of Toll-l...

Peptidoglycan Fragment Release from Neisseria meningitidis [Bacterial Infections] 14 Aug 2013 | 12:54 am

Neisseria meningitidis (meningococcus) is a symbiont of the human nasopharynx. On occasion, meningococci disseminate from the nasopharynx to cause invasive disease. Previous work showed that purified ...

Articles of Significant Interest Selected from This Issue by the Editors [Spotlight] 14 Aug 2013 | 12:54 am

Animal Models for Studying Female Genital Tract Infection with Chlamydia trachomatis [Minireviews] 14 Aug 2013 | 12:54 am

Chlamydia trachomatis is a Gram-negative obligate intracellular bacterial pathogen. It is the leading cause of bacterial sexually transmitted disease in the world, with more than 100 million new cases...

Characterization of Intracellular Growth Regulator icgR by Utilizing Transcriptomics To Identify Mediators of Pathogenesis in Shigella flexneri [Molec... 14 Aug 2013 | 12:54 am

Shigella species Gram-negative bacteria which cause a diarrheal disease, known as shigellosis, by invading and destroying the colonic mucosa and inducing a robust inflammatory response. With no vaccin...