H-NS Is a Novel Transcriptional Modulator of the Ribonucleotide Reductase Genes in Escherichia coli [Articles] 27 Aug 2013 | 12:40 am

Ribonucleotide reductases (RNRs) are essential enzymes for DNA synthesis because they are responsible for the production of the four deoxyribonucleotides (dNTPs) from their corresponding ribonucleotid...

Identification and Characterization of Clostridium sordellii Toxin Gene Regulator [Articles] 27 Aug 2013 | 12:40 am

Toxigenic Clostridium sordellii causes uncommon but highly lethal infections in humans and animals. Recently, an increased incidence of C. sordellii infections has been reported in women undergoing ob...

Genome-Wide Transcriptional Profiling of the Purple Sulfur Bacterium Allochromatium vinosum DSM 180T during Growth on Different Reduced Sulfur Compoun... 27 Aug 2013 | 12:40 am

The purple sulfur bacterium Allochromatium vinosum DSM 180T is one of the best-studied sulfur-oxidizing anoxygenic phototrophic bacteria, and it has been developed into a model organism for laboratory...

Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydi... 27 Aug 2013 | 12:40 am

Salicylidene acylhydrazides (SAHs) inhibit the type III secretion system (T3S) of Yersinia and other Gram-negative bacteria. In addition, SAHs restrict the growth and development of Chlamydia species....

Evidence for a Key Role of Cytochrome bo3 Oxidase in Respiratory Energy Metabolism of Gluconobacter oxydans [Articles] 27 Aug 2013 | 12:40 am

The obligatory aerobic acetic acid bacterium Gluconobacter oxydans oxidizes a variety of substrates in the periplasm by membrane-bound dehydrogenases, which transfer the reducing equivalents to ubiqui...

Initiation with Elongator tRNAs [Articles] 27 Aug 2013 | 12:40 am

In all domains of life, initiator tRNA functions exclusively at the first step of protein synthesis while elongator tRNAs extend the polypeptide chain. Unique features of initiator tRNA enable it to p...

Functional Interactions of VirB11 Traffic ATPases with VirB4 and VirD4 Molecular Motors in Type IV Secretion Systems [Articles] 27 Aug 2013 | 12:40 am

Pilus biogenesis and substrate transport by type IV secretion systems require energy, which is provided by three molecular motors localized at the base of the secretion channel. One of these motors, V...

Characterization of a Novel RNA Polymerase Mutant That Alters DksA Activity [Articles] 27 Aug 2013 | 12:40 am

The auxiliary factor DksA is a global transcription regulator and, with the help of ppGpp, controls the nutritional stress response in Escherichia coli. Although the consequences of its modulation of ...

Acetylation of the Response Regulator RcsB Controls Transcription from a Small RNA Promoter [Articles] 27 Aug 2013 | 12:40 am

N-lysine acetylation was recently discovered on many bacterial proteins that function in diverse cellular processes. Thus, many questions remain unanswered. For example, what mechanisms regulate lysin...

Editorial Board [Masthead] 27 Aug 2013 | 12:40 am