Physiology - ajpregu.physiology.org
General Information:
Latest News:
Cannabinoid 1 receptors are critical for the innate immune response to TLR4 stimulation 1 Aug 2013 | 09:00 pm
Sickness behaviors are host defense adaptations that arise from integrated autonomic outputs in response to activation of the innate immune system. These behaviors include fever, anorexia, and hyperal...
A high-grain diet causes massive disruption of ruminal epithelial tight junctions in goats 1 Aug 2013 | 09:00 pm
Alterations in rumen epithelial tight junctions (TJs) at the tissue and molecular levels during high-grain (HG) diet feeding are unknown. Here, 10 male goats were randomly assigned to either a hay die...
Proton-facilitated ammonia excretion by ionocytes of medaka (Oryzias latipes) acclimated to seawater 1 Aug 2013 | 09:00 pm
The proton-facilitated ammonia excretion is critical for a fish's ability to excrete ammonia in freshwater. However, it remains unclear whether that mechanism is also critical for ammonia excretion in...
Speed and accuracy of taste identification and palatability: impact of learning, reward expectancy, and consummatory licking 1 Aug 2013 | 09:00 pm
Despite decades of study, it remains a matter of controversy as to whether in rats taste identification is a rapid process that occurs in about 250–600 ms (one to three licks) or a slow process that e...
Estradiol modulates recovery of REM sleep in a time-of-day-dependent manner 1 Aug 2013 | 09:00 pm
Ovarian hormones are thought to modulate sleep and fluctuations in the hormonal milieu are coincident with sleep complaints in women. In female rats, estradiol increases waking and suppresses sleep. I...
Effect of extraluminal ATP application on vascular tone and blood flow in skeletal muscle: implications for exercise hyperemia 1 Aug 2013 | 09:00 pm
During skeletal muscle contractions, the concentration of ATP increases in muscle interstitial fluid as measured by microdialysis probes. This increase is associated with the magnitude of blood flow, ...
Morphometric analysis of gastrocnemius muscle biopsies from patients with peripheral arterial disease: objective grading of muscle degeneration 1 Aug 2013 | 09:00 pm
Peripheral arterial disease (PAD), which affects ~10 million Americans, is characterized by atherosclerosis of the noncoronary arteries. PAD produces a progressive accumulation of ischemic injury to t...
Lack of conventional oxygen-linked proton and anion binding sites does not impair allosteric regulation of oxygen binding in dwarf caiman hemoglobin 1 Aug 2013 | 09:00 pm
In contrast to other vertebrate hemoglobins (Hbs) whose high intrinsic O2 affinities are reduced by red cell allosteric effectors (mainly protons, CO2, organic phosphates, and chloride ions), crocodil...
Leg oxygen uptake in the initial phase of intense exercise is slowed by a marked reduction in oxygen delivery 1 Aug 2013 | 09:00 pm
The present study examined whether a marked reduction in oxygen delivery, unlike findings in moderate-intensity exercise, would slow leg oxygen uptake (V o 2) kinetics during intense exercise (86 ± 3%...
