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Count-based differential expression analysis of RNA sequencing data using R and Bioconductor 27 Aug 2013 | 04:49 pm

RNA sequencing (RNA-seq) has been rapidly adopted for the profiling of transcriptomes in many areas of biology, including studies into gene regulation, development and disease. Of particular interest ...

Featured RNA-Seq Job – SENIOR BIOINFORMATICS SPECIALIST – Tufts Technology Services 27 Aug 2013 | 04:44 pm

Tufts University Job Location: Somerville, MA Job Category: Information systems / technology Posted: August 14 Tufts Technology Services (TTS) is a university-wide service organization dedicated t...

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RNA-Seq Blog – Poll Results rna-seqblog.com 23 Aug 2013 | 05:48 pm

We asked – What is the optimal sequencing length (cycles) for RNA-Seq experiments? Total of 118 respondents. Thanks to all who participated in the last poll.  Check out our latest poll in the right ...

Whole-Transcriptome Shotgun Sequencing (RNA-seq) Screen Reveals Upregulation of Cellobiose and Motility Operons of Lactobacillus ruminis L5 during Gro... aem.asm.org 21 Aug 2013 | 11:35 pm

Lactobacillus ruminis is an inhabitant of human bowels and bovine rumens. None of 10 isolates (three from bovine rumen, seven from human feces) of L. ruminis that were tested could utilize barley β-gl...

New data tracks added to GBrowse yeastgenome.org 21 Aug 2013 | 03:10 am

SGD has added new data tracks to the GBrowse genome viewer covering differential expression RNA-seq data from Waern & Snyder (2013) and Transcript Leader RNA-seq data from Arribere & Gilbert (2013). ...

New data tracks added to GBrowse db.yeastgenome.org 21 Aug 2013 | 03:10 am

SGD has added new data tracks to the GBrowse genome viewer covering differential expression RNA-seq data from Waern & Snyder (2013) and Transcript Leader RNA-seq data from Arribere & Gilbert (2013). ...

TIGAR: transcript isoform abundance estimation method with gapped alignment of RNA-Seq data by variational Bayesian inference bioinformatics.oxfordjournals.org 27 Aug 2013 | 11:48 am

Motivation: Many human genes express multiple transcript isoforms through alternative splicing, which greatly increases diversity of protein function. Although RNA sequencing (RNA-Seq) technologies ha...

Inference of alternative splicing from RNA-Seq data with probabilistic splice graphs bioinformatics.oxfordjournals.org 27 Aug 2013 | 11:48 am

Motivation: Alternative splicing and other processes that allow for different transcripts to be derived from the same gene are significant forces in the eukaryotic cell. RNA-Seq is a promising technol...

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor rna-seqblog.com 27 Aug 2013 | 04:49 pm

RNA sequencing (RNA-seq) has been rapidly adopted for the profiling of transcriptomes in many areas of biology, including studies into gene regulation, development and disease. Of particular interest ...

Featured RNA-Seq Job – SENIOR BIOINFORMATICS SPECIALIST – Tufts Technology Services rna-seqblog.com 27 Aug 2013 | 04:44 pm

Tufts University Job Location: Somerville, MA Job Category: Information systems / technology Posted: August 14 Tufts Technology Services (TTS) is a university-wide service organization dedicated t...

tweeDEseq: a test for differential expression based on the Poisson-Tweedie family rna-seqblog.com 26 Aug 2013 | 05:00 pm

High-throughput RNA sequencing (RNA-seq) offers unprecedented power to capture the real dynamics of gene expression. Experimental designs with extensive biological replication present a unique opportu...

Whole transcriptome RNA-Seq allelic expression in human brain rna-seqblog.com 26 Aug 2013 | 04:49 pm

Measuring allelic RNA expression ratios is a powerful approach for detecting cis-acting regulatory variants, RNA editing, loss of heterozygosity in cancer, copy number variation, and allele-specific e...

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